New Psoriasis Treatment Guideline Integrates All Approved Systemic Therapies
Berlin, Germany - The German Dermatological Society (DDG) has released an updated S3 guideline for the treatment of psoriasis vulgaris, integrating all currently approved systemic therapies to optimize patient care and mitigate cardiovascular risks. The guideline, available as of July 2025, adapts recommendations from the Euroguiderm Guideline on systemic psoriasis treatment and incorporates the latest findings from a Cochrane network meta-analysis.
psoriasis affects millions globally, and systemic treatments – medications that work throughout the body - are often necessary for moderate to severe cases. This updated guideline aims to provide dermatologists with a comprehensive, evidence-based framework for selecting the most appropriate systemic therapy for each patient, considering both efficacy and potential side effects, including the increased risk of cardiovascular diseases. The guideline’s release comes as new data reveals a important prevalence of psoriasis and psoriatic arthritis in Germany, impacting a considerable portion of the population.
The guideline’s foundation rests on the current Cochrane network meta-analysis by Sbidian et al. (published August 6, 2025), which evaluates the effectiveness of various systemic pharmacological treatments for chronic plaque psoriasis. It also references the german Dermatological Society’s (DDG) S3 guideline “Treatment of psoriasis vulgaris” (AWMF registration number 013 – 001), version 8.0.A recent analysis by Hagenström, Müller, Garbe, and Augustin (January 2024) in Journal of the German Dermatological Society highlighted the prevalence of psoriasis and psoriatic arthritis in Germany based on claims data.
The DDG emphasizes the importance of a tailored approach to treatment,acknowledging that the optimal therapy varies depending on individual patient characteristics and disease severity. Further data is available on the DDG website at https://www.derma.de and details regarding the KoPra 2026 conference can be found at https://www.derma-tagungen.de.
Contact:
Prof.Dr. med. silke Hofmann
Public Relations Officer, German Dermatological Society (DDG)
Dagmar Arnold, press Office
Tel.: +49 30 246 253-35
E-Mail: d.arnold(at)derma.de
