## Root Canal Treatment Linked to Improved Metabolic Health, New Research Shows
Root canal treatment, often surrounded by outdated fears and myths and misconceptions, may offer broader health benefits than simply resolving tooth pain, according to a recent study. The procedure addresses infection or damage to the pulp - the inner tissue of a tooth containing nerves, blood vessels, and connective tissue.
Researchers at Guy’s and St Thomas’ NHS foundation trust in London tracked 65 patients for two years following root canal treatment. They analyzed blood samples taken before the procedure and at four subsequent points to assess how patients processed sugars, fats, and other substances. The study,published in the Journal of Translational Medicine, revealed critically important changes in over half of the blood molecules analyzed.
The findings indicate short-term improvements in fat metabolism and long-term improvements in blood sugar levels following the dental work. Importantly, markers of inflammation – a key driver in many chronic diseases – were also observed to decrease after the root canal treatment.
This research builds on the understanding that long-standing tooth infections can allow bacteria to enter the bloodstream, perhaps increasing inflammation and impairing blood sugar control. However, this study demonstrates benefits *beyond* simply eliminating the infection. “It’s not about treating the single tooth. This has long-term benefits on the general health of the patient, particularly the risk of chronic conditions like heart disease and diabetes,” explained researcher Dr. Zia Niazi.
The prevalence of root canal treatment is considerable. A 2024 public health survey in England showed that more than a third of adults have undergone the procedure, rising to 50% among those aged 55-74. In the US, over 15 million root canal procedures are performed annually.
these findings underscore the importance of oral health as a gateway to overall wellbeing. Niazi emphasized, “People must understand that your mouth is the main gateway to your general health, so looking after your oral health and doing regular checkups with your dentist and getting disease treated early is the best course of action.”
The research is particularly relevant given the global burden of untreated oral disease. The World Health Institution estimates that 3.7 billion people worldwide live with untreated oral conditions. Integrating oral health into broader healthcare strategies is crucial, Niazi argues.
This study complements recent research highlighting the link between oral health and systemic disease. A clinical trial at University College London, published a week prior, found that treating severe gum disease could prevent arteries from becoming clogged, reducing the risk of heart disease and stroke – also through a reduction in inflammation. Dr. Marco Orlandi, a co-principal investigator on that trial, noted that oral conditions are associated with a range of non-communicable diseases and should be considered a “non-customary risk factor” for clogged arteries.
