Vaccines work in most patients with autoimmune disease

Groningen – Professor of Vaccinology Anke Huckriede of the University of Groningen, RuG, calls it cautiously positive that vaccines seem to work in patients with an autoimmune disease.

Researchers from Amsterdam UMC and blood bank Sanquin have conducted research into the effects of the corona vaccine on patients with an autoimmune disease who use immunosuppressive drugs. These are the first results of an extensive national study. According to the researchers, it is good news for the approximately 800,000 patients with rheumatism, lung, skin or kidney diseases. Until now, it was assumed that they respond less well to corona vaccines due to the use of immune inhibitors. The study does show that it only applies to some of the drugs.

Wait and see if immune response persists
Huckriede was not involved in the investigation. She says she is cautiously positive about the first results. However, it is still too early to draw conclusions. “Now we have to wait and see how long the immune response lasts. If there is also a good response immediately in people who do use immune inhibitors, then I think there are good chances that they will also be protected against the virus in the long term.” Says on Sunday morning.

3,000 participants
3,000 participants participated in the study. The preliminary results are based on data from the first 1,500 participants. The study only looked at patients with an autoimmune disease. This does not include people with, for example, blood cancer, HIV, or Down syndrome or transplant patients. Last month it became clear about this group that some of them do not produce antibodies and immune cells after vaccination. The full study will be published next month.



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