Published on : 05/15/2020 – 16:51
Two studies published in the British Medical Journal show that the molecule does not improve patients with SARS-CoV-2.
While the toll of the coronavirus pandemic has exceeded the 300,000 death mark in the world and that laboratories are still working on the development of a vaccine, the scientific community was able to discover, Friday May 15, the results of two robust methodology studies conducted onhydroxychloroquine, a molecule presented as a possible treatment against Covid-19. They were published in the British medical journal British Medical Journal (BMJ).
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“ The results do not encourage the use of hydroxychloroquine “
The first study is French and was based on the observation of 182 patients with a form of Covid-19 requiring oxygen administration. These patients were divided into two groups: one received hydroxychloroquine as a treatment and was compared to the second control group, which received the usual standard of care. The objective was to quantify the number of patients dying or requiring care in the intensive care unit according to the two groups.
The result is clear: whether or not patients receive hydroxychloroquine, the consequences are similar. The authors conclude: ” The results of this study do not support the use of hydroxychloroquine for patients with Covid-19 admitted to hospital when they need oxygen. “
” more serious side effects ”
The second study, a Chinese woman, was studying the rate at which the virus was cleared in patients with mild to moderate disease.
This time, 150 patients participated, again divided into two groups: one receiving hydroxychloroquine, the other receiving standard care. As with the first study, the authors found no difference between the two groups: ” The administration of hydroxychloroquine did not significantly increase the likelihood that patients would reduce their viral load compared to standard treatments. “
More annoying, the authors note that ” side effects were greater in those who received hydroxychloroquine ” Thus, in the control group, 9% of patients paid the price, while they were 30% in the treated group. The majority of them suffered from diarrhea.
These two studies thus provide several robust elements indicating an ineffectiveness of hydroxychloroquine against Covid-19. Results that ” do not advocate its use as a routine treatment for illness “, Write the British Medical Journal in a press release.
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