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This is Different from Efficacy and Effectiveness, Determinants of Vaccine Quality

Report from Tribunnews.com Journalist, Rina Ayu

TRIBUNNEWS.COM, JAKARTA – The terms efficacy and effectiveness have become familiar during the Covid-19 pandemic.

Both are often associated with vaccines, namely as a determinant of vaccine quality.

Head of the Eijkman Institute for Molecular Biology (LBM) Prof. Amin Subandrio said that the two terms are often considered the same, although in fact they are somewhat different.

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“The current term varies slightly between efficacy and effectiveness,” he said some time ago.

Amin explained that efficacy is a measurement result obtained after clinical trials, where the numbers are obtained from the results of clinical trials.

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“In clinical trials everything is controlled, starting from the subject, which vaccine is injecting under controlled, all conditions are controlled. So that the expected conditions are ideal,” he explained.

Meanwhile, effectiveness is measured after the vaccine is marketed or given to the public, meaning that all subjects and conditions are no longer ideal.

“Our subjects do not know, are not registered, the condition of the vaccine is also not necessarily stable because of the distribution channel. So the effectiveness is obtained from when vaccinating,” said Amin.

“So that’s the difference between efficacy and effectiveness,” he added.

He emphasized, even though the vaccine has been completed clinical trials and given to the community, monitoring on quality and safety is carried out regularly.

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