The miracle pill that weakens you just by sitting on the couch. The opinion of specialists

Two researchers say they have discovered a cure for obesity that, in addition to reducing appetite and feeling hungry, could help keep you fit without the need for exercise.

For now, this is a study done on laboratory mice.

The fat cure is called Lac-Phe and is actually a molecule that could fight obesity by reducing your intake of food and the feeling of hunger, is shown in an article published in ilmessaggero.it.

Moreover, according to those who discovered this molecule, you may no longer need to go to the gym.

Goodbye diet? What researchers who discovered the “miracle” pill say

Goodbye, diet? It’s not a joke, it’s all true, say two researchers from the most prestigious universities in the United States.

“It has been shown that exercise can help you lose weight weight – says Yong Xu, one of the leaders of the works – by understanding the mechanism by which physical activity triggers these benefits, we could help many people find their shape quickly and without excessive effort.

For now, studies are in the laboratory mouse stage, but – as is often the case when a new drug is being tested – good results in animal testing are a step ahead of humans.

From experiments, Lac-Phe drastically reduces food intake and obesity in guinea pigs. And, according to scientists, it could also replace the need for subjects to go to the gym.

Jonathan Long, a colleague of Young Xi, says that “for example, the elderly or frail could benefit from a drug that helps fight osteoporosis, heart disease and a number of problematic conditions.” The results, published in the journal Nature, also shed new light on the links between exercise and hunger.

“We are all aware that exercise is good for our health. It’s useful for controlling body weight and glucose, “Long continues,” But we wanted to delve deeper into the concept: we wanted to see if we could dissect the exercise in terms of molecules. “

How the miracle molecule was discovered

Thus, the scientists analyzed the blood plasma of the mice after an intense run on the treadmill. From here we identified an amino acid called Lac-Phe, a synthesized from lactate, a by-product associated with intense exercise, responsible for the burning sensation in the muscles, and from phenylalanine, a block of proteins.

The rodents examined, all obese, followed a high-fat diet but with a high dose of Lac-Phe led them to reduce their food intake by 50%. No side effects were observed on the ability to move or on energy consumption. Not only. The benefits continue. After 10 days of administration of Lac-Phe, the guinea pigs were less hungry and had reduced body fat, as well as better glucose tolerance.

Experts have also identified CNDP2, an enzyme involved in the production of Lac-Phe. In fact, mice with low levels of this enzyme did not lose so much weight, despite a strict exercise pattern. “These first results,” Xu concludes, “are really interesting. Our goal is to learn how to modulate these compounds to give the body the same benefits associated with physical activity.

Nutritionist: “there is no such thing as sitting on the couch, taking a pill and, suddenly, increasing your sports performance

Nutritionist Șerban Damian commented for Ziare.com that “there are all kinds of nutritional supplements with various effects.

If we talk about weight loss are the substances that are said to accelerate to some extent metabolism. But most studies say the effect is insignificant. There is no significant difference that really matters.

On the other hand, there are substances that help by enhancing the ability to make an effort. For example, it is creatine, a substance with an energetic role in the body and can help you do more intense workouts and have better sports results. It rapidly increases your available energy stores.

But in this way. There is no sitting on the couch, taking a pill and, suddenly, your sports performance increases.

To the best of my knowledge, there is no substance to replace or mimic the effects of physical activity.

There are nutritional supplements that enhance the body’s ability to make physical effort and thus get better results, “said Dr. Serban Damian, sports nutritionist.

Marius Geantă: We have to consider that it is a pre-clinical study

On the other hand, Dr. Marius Geantă, president of the Center for Innovation in Medicine, says that in this case several aspects must be taken into account.

“Of course, the results of the study are promising, but we must take into account that we are talking about a pre-clinical study. That is, there is not necessarily a guarantee that these results can be translated into people on a topic such as obesity.Said the doctor.

There is a big difference between studying in the lab and what can happen in reality.

“One is to monitor the phenomenon of obesity in animals, especially laboratory and small animals and another is to monitor obesity in humans. In the development of obesity in humans, including morbid obesity, many more factors are involved than those that are taken into account in the laboratory on such animal models.

In real life, social factors and the educational model also matter a lot, the availability of quality food on the one hand, and the desire of people to do physical activity on the other.

I think it’s a misconception that this pill could replace exercise. What we need to say is that in cases of morbid obesity the impact of exercise is limited. It has a role to play but we cannot say that we can replace exercise as the main tool in the fight against morbid obesity with a pill. It is an exaggerated statement “, explains the public health specialist.

Obesity also comes with many complications

The doctor also brings to the fore the fact that morbid obesity is linked to a number of complications that are not solved by a pill alone. And one of the most viable solutions today is surgery.

“What we know about morbid obesity is that in addition to a large number of extra pounds, it comes with many cardio-metabolic complications. There are people who have diabetes associated with diabetes, are people who have cardiovascular disease or certain types of cancer with higher frequency.

We are talking about a special subgroup that is still not very well understood from a pathogenic point of view, from the point of view of the transition to this morbid obesity. Obviously there are biological factors involved here, genes or pathways that are altered but individual behavior also matters because these extra pounds and the associated cardio-metabolic risks do not occur overnight.

But if we are talking about the management of a patient with morbid obesity, at this moment we are talking about a solution about metabolic bariatric surgery. There are several types of surgery but their effect is to help the person to lose weight, to reduce the risk of diabetes, heart attack and cardiovascular disease.

But after the operation, the person must change your lifestyle and accept that from that moment we are talking about a chronic disease and will have to fight with it for a long time, maybe even until the end of life “, the specialist also explained.

In our country, such surgeries are not reimbursed by our health insurance system. In other countries it has been understood that this disease is not just a matter of physical appearance.

“The obesity market will develop in the coming years. There are already a number of drugs that are already approved in Europe.

But it should not be said that these drugs can replace a balanced diet, but they can be recommended under certain conditions by doctors. We must not transmit the illusion that there is a miracle pill that solves the problem “, said Dr. Marius Geantă.

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