NFL Week 5 Picks, Predictions & Odds: Experts Weigh In
As week 5 of the NFL season approaches, analysts are releasing their predictions adn assessing the latest odds, with several key matchups poised to shake up the league standings. Updated injury reports for games like Colts vs. Raiders are influencing betting lines and expert picks, while the performance of forecasters is being closely tracked.
This week’s selections come as teams navigate early-season challenges and contenders begin to emerge. USA TODAY Sports’ panel of experts-Blake Schuster, Jon Hoefling, Tyler Dragon, Lorenzo Reyes, Chris Bumbaca, Jordan Mendoza, and Richard Morin-are offering their insights against the spread. Beyond individual game predictions, attention is also turning to the long-term outlook, with updated odds for Super Bowl 60 already available.
Expert Pick Records (Through Week 4):
* Blake Schuster: 10-5-1 (34-27-3 overall)
* Jon Hoefling: 7-8-1 (33-28-3 overall)
* Tyler Dragon: 8-7-1 (33-28-3 overall)
* Lorenzo Reyes: 5-10-1 (30-31-3 overall)
* Chris Bumbaca: 6-9-1 (30-31-3 overall)
* Jordan Mendoza: N/A (24-22-2 overall)
* Richard Morin: 9-6-1 (9-6-1 overall)
Super Bowl 60 Odds: odds were last updated October 1, 2025.
The Los Angeles Rams defense is also a focal point as analysts evaluate team strengths and weaknesses heading into Week 5.
