Home » Health » Scientists have found the cause of severe complications from COVID-19 in antibodies – Rambler / doctor

Scientists have found the cause of severe complications from COVID-19 in antibodies – Rambler / doctor

Scientists at the Massachusetts Institute of Technology in the United States have revealed why COVID-19 passes differently in different patients.

The reason has to do with the types of antibodies that cause unwanted reactions. This is reported by the publication Nature Medicine.

Experts have shown that children with MIS-C, which developed after COVID-19, have high levels of IgG antibodies. Usually antibodies help control infection, but in the case of MIS-C, these antibodies activate immune cells.

IgGs interact with macrophages, increasing their activity. Due to the fact that macrophages are present in many tissues, the inflammatory process begins.

Adults with severe COVID-19 have elevated levels of IgA antibodies, which interact with neutrophils and cause them to secrete cytokines. If there are too many IgA antibodies, it can cause a cytokine storm.

The researchers hope the discovery will help develop therapies that alter the immune response while preserving its protective functions and reducing harmful responses.

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