Suara.com – In April, the study found 33 Corona virus mutation (Covid-19) which shows mutations quickly. Para the scientist believes that viruses can increase their infectivity.
Viral mutations occur through random events that can have a number of effects. The team of experts from the Scripps Research Institute found that mutations in the dominant Covid-19 virus strain in the West, called G614, have multiplied more and transmitted more efficiently to other hosts.
This mutation appears to compensate for the previous weakness held by the original strain (D614) in which the structure outside the virus, called a spike protein, will be interrupted when attached to human airway cells.
Spike proteins are involved in attaching viral cells to host cells, where viruses can infect and multiply cells before releasing and finding new hosts. If the new strain has a mutation that helps it maintain the spike protein, it can multiply and infect the new host at an increasing rate.
Scientists believe the mutation strain G614 has a more stable spike protein than the D614 strain. Allegedly, this new strain is about 10 times more infectious than before.
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Surprisingly, an increase in infectivity is not seen along with an increase in disease severity. Despite an increase in transmission, patients infected with G614 have no more severe effects or symptoms compared to patients infected with D614.
The mutation found by the Scripps team correlates with research released by the University of Sheffield in April, which showed that mutations accumulated in the virus through positive selection. In the G614 mutation strain region, scientists noted a rapid increase in the frequency of the strain and it was able to become the dominant strain in just a few weeks.
Even so, this research is still a precast study so it has not been reviewed by colleagues.
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“Corona viruses produce mutations as part of their normal replication. Some of them will affect the nature of the virus,” said professor Ian Jones, a virologist at the University of Reading, who was not involved in the study.
Reporting from IFL ScienceOn Friday (3/7/2020), some scientists believe the Corona virus mutation might add some challenges to making vaccines because mutations can change how effectively human immune cells can recognize viral infections.
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