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Passive smoking, breast cancer – Norwegian researchers with groundbreaking findings

It has long been known that not only smoking but also passive smoking increases the risk of lung cancer and heart attack.

Now, researchers at the University of Tromsø have found that girls who were exposed to passive smoking in childhood have an increased risk of developing breast cancer several decades later, writes Forskning.no.

The Norwegian researchers make no secret of the fact that they have made groundbreaking discoveries, in studies which is published in the renowned medical journal International Journal of Epidemiology.

“As far as we know, our study is the first to estimate the proportion of breast cancer in never-smokers that can be attributed to exposure to passive smoking from parents in childhood,” the researchers write.

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1 out of 10

The study includes a total of 45,923 women who have never smoked themselves, born between 1929 and 1957. Two thirds of them had been exposed to passive smoking in childhood.

2185 of the women were diagnosed with breast cancer within 27 years.

1493 (243/100 000) of the women who got breast cancer were among those who had been exposed to passive smoking by the parents in childhood, while only 692 (217/100 000) breast cancer cases occurred among those who answered that they had not been exposed to this.

If you only look at the group that was exposed to their parents’ smoking in childhood, the researchers find that one in 10 cases of breast cancer can be attributed to this exposure.

For the entire study population of close to 46,000 women, the researchers find that one in 14 breast cancer cases can be linked to passive smoking in childhood.

This corresponds to seven percent of all breast cancer cases, and is a serious finding, considering that breast cancer is the most common form of cancer among women in Norway and the most common cancer of all worldwide.

According to figures from the Cancer Registry, 3424 women in Norway were diagnosed with breast cancer in 2020.

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– Surprised

– Biologically speaking, we had expected to find a small increase in the number of breast cancer cases, because with passive smoking you are exposed to many of the same carcinogens as with smoking. The breast tissue is very exposed to the influence of carcinogens before and during development during puberty, says professor at UiT Norway’s Arctic University and first author of the study, Inger Torhild Gram, to Dagbladet.

She adds:

– We were surprised to find such a strong connection that we found between passive smoking and breast cancer, says Gram.

The researchers checked their analyzes for age and other established risk factors for breast cancer, so that they could be compared directly. These factors include the number of children, age at first birth, high BMI, alcohol intake and breast cancer in the immediate family, the professor says.

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– Positive

In the recent research article, the researchers write that it is a strength of the study that they have looked at a large number of cases of breast cancer that have arisen after known exposure to passive smoking from parents in childhood, in a population of women who have never smoked.

– There is definitely something positive in our findings. It is possible to do something about children being exposed to passive smoking. In Norway, we have come a long way when it comes to this, so one can gradually expect to see a decline in Norwegian breast cancer cases since children today are less exposed to passive smoking, says Gram.

She is pleased that their research article has been published in a prestigious journal such as the International Journal of Epidemiology.

– We would like our study to be read in parts of the world where there is a high proportion of daily smokers, says Gram.

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