Sunday, December 7, 2025

Parkinson’s Disease: Predicting Cognitive Decline Through Smell Loss

“I Can’t Smell Well‌ These Days…” – A diminished Sense of Smell May Signal Parkinson’s Disease

Recent data from the Korea ​Disease Control and Prevention Agency (KDCA) ⁣and the National Institute of health‌ reveals a concerning rise in⁣ Parkinson’s disease cases within the country. The number ‌of patients increased by 13.9% over four years, climbing from 125,927 in 2020 to 143,441 in 2023. This increase is directly linked to Korea’s aging population, with ​the majority of patients⁣ falling into the 60s (18.7%,or 20,819⁣ people),70s (37.9%, or 42,172 people), and ‌80s or older (36.5%, or 40,603 people).

Recognizing the urgent need for improved⁣ diagnosis ‌and treatment,‍ the National Institute of Health launched the ‘Brain⁣ Disease Research Base Creation Research⁣ Project’ in⁤ 2021. This ‍initiative,⁤ conducted in collaboration with universities and medical institutions, focuses on⁤ long-term patient follow-up to better understand the disease’s diagnosis, ⁤prevention, and potential progression.‍ Currently, the exact ‌cause ‍of Parkinson’s remains unknown, and definitive diagnostic tests ‍are lacking, making research crucial.

A⁤ recent study stemming from this project has uncovered ⁢a⁤ surprising link between olfactory function (sense of smell) and‍ cognitive‍ decline in⁣ parkinson’s patients. Researchers tracked 203 patients over five years,⁣ categorizing them ⁤based ​on their sense of smell – normal, reduced, or deteriorated. The study found that a significant majority (85.7%) experienced a loss of smell during ⁣the follow-up period. Notably,those who initially had ⁢a normal sense of smell experienced a faster rate of cognitive decline.

This finding is significant ⁣because⁢ olfactory function tests are ​relatively simple to administer. Researchers believe this could lead to earlier diagnosis of Parkinson’s disease and more accurate predictions of cognitive⁤ decline. ⁤As one researcher stated,detecting even subtle⁣ changes like difficulty smelling could be‌ instrumental in early screening and the progress of personalized treatment plans.

To aid in awareness and early detection,⁣ researchers have developed the ⁤mobile app ‘Dr. Parkinson’ ‌to provide ‌accessible self-diagnosis information. This is notably ‌vital given that a survey revealed 26% of Parkinson’s patients initially received incorrect treatment after misdiagnosing their symptoms as something else. Individuals experiencing suspicious symptoms – such as muscle stiffness, tremors in the hands and feet, or ⁤slow movements‌ – are strongly ​advised to consult ‌a neurologist.

Lim seung-gwan,Director of the Korea Disease Control⁤ and Prevention Agency,emphasized the agency’s commitment ⁣to unraveling the complexities of Parkinson’s disease. “The Korea Disease Control and Prevention Agency is working to identify the cause of the disease⁢ and develop precise diagnosis technology through Parkinson’s disease patient ⁤cohorts and intervention studies,” he stated. ‍”We will strive ⁣to lead‍ to research results that patients can feel in the future.”

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