Finnish Research Suggests Omega-3 Supplement Risks Require Further Evaluation
helsinki, Finland – September 13, 2025 – A new study from teh University of Helsinki indicates that long-term use of omega-3 polyunsaturated fatty acid (PUFA) supplements may be associated with increased risk of certain cardiovascular events in individuals with pre-existing heart disease. The research, published today, challenges widely held beliefs about the global benefits of these popular supplements and calls for a more nuanced understanding of their impact on heart health.
The study,involving over 2,500 participants with established coronary artery disease,followed individuals for an average of five years. Researchers found no overall benefit from omega-3 supplementation and, surprisingly, observed a statistically notable increase in the incidence of atrial fibrillation – an irregular heartbeat – among those taking daily omega-3 supplements. This finding is particularly relevant given the widespread use of omega-3s, often self-prescribed, by individuals seeking to protect their cardiovascular health.
“our findings suggest that the blanket recommendation of omega-3 supplementation for all individuals, particularly those with existing heart conditions, may need to be re-evaluated,” stated Dr. A. Järvinen, lead author of the study and professor of cardiology at the University of Helsinki. ”While omega-3 fatty acids are essential nutrients, the form and dosage, and also the individual’s underlying health status, appear to play a critical role in determining their effects.”
The research team emphasizes that the study does not suggest that individuals consuming omega-3s through diet – such as fatty fish like salmon and mackerel – should alter their eating habits.the observed risks were specifically linked to concentrated doses of omega-3s found in supplement form.
Researchers are now planning follow-up studies to investigate the specific mechanisms driving the observed association between omega-3 supplementation and atrial fibrillation. They also intend to explore whether different types of omega-3 fatty acids (EPA, DHA, ALA) have varying effects on cardiovascular health. The findings underscore the importance of personalized medicine and the need for individuals to discuss the potential risks and benefits of supplements with their healthcare providers before initiating long-term use.
