Laughing Gas Shows Promise as Rapid Treatment for Depression,New Review Finds
BIRMINGHAM,UK – A thorough review of existing research suggests nitrous oxide,commonly known as laughing gas,may offer rapid relief for individuals with treatment-resistant depression,though experts caution significantly more research is needed. The study, published recently, indicates potential for the gas as an ”added treatment option” for patients who haven’t responded to conventional therapies.
Currently, depression affects millions worldwide, and finding effective treatments can be a lengthy and challenging process. While nitrous oxide has long been used as a pain reliever in medical settings, its potential as a psychiatric treatment is only beginning to be explored.
The review, led by Steven Marwaha, professor of psychology at the University of Birmingham, analyzed available data on nitrous oxide’s effects on depression. Marwaha stated, “This is a notable milestone in understanding the potential of nitrous oxide as an added treatment option for patients with depression who have been failed by current treatments.”
However, Professor Hamish McAllister-Williams of newcastle university, who was not involved in the review, emphasized the limitations of the current evidence. ”This is a very well conducted and comprehensive review of currently available data… However, as the authors point out, the data is far from demonstrating that nitrous oxide is a viable treatment for depressive illness.”
McAllister-williams pointed out that the trials included in the review were small, varied in their submission of the treatment, were of short duration, and involved diverse patient groups.He also noted concern that patients in many studies were able to guess whether they received nitrous oxide or a placebo, potentially skewing results. “this review suggests that it is worthwhile looking further into whether nitrous oxide may be a treatment for depression, but that much more research is needed with larger and better designed trials before any conclusions can be drawn.”
Alongside the potential therapeutic benefits, the review highlights growing concerns about the recreational misuse of nitrous oxide. The gas is increasingly popular among 16 to 24-year-olds – becoming the second most used recreational drug after cannabis – and is often obtained from whipped cream dispensers. Doctors are reporting a rise in cases of nerve damage, bladder problems, and blood issues linked to overuse of the gas.
