Trials of the Covid-19 vaccine in Russia began in mid-summer. In addition to Russian Sputnik V volunteers, the Chinese company CanSino Biologics Inc. is also injected. developed preparation. Anastasia Jefremova, the editor of the portal “rus.delfi.lv”, who is currently in St. Petersburg, decided to try the vaccine for herself and tell readers how it happens.
The Ad5-nCov vaccine was developed by the Chinese company CanSino Biologics Inc. in collaboration with the Beijing Institute of Biotechnology and the Military Medical Academy. I could also say that it is a recombinant vaccine based on an adenovirus vector, but I am not a doctor, so I will try to describe the mechanism of action of the vaccine in my own words.
Viruses cannot multiply by dividing cells, so they use cells from other organisms to multiply. They “reprogram” the captured cell and turn it into the same virus factory. Immunity recognizes the virus by specific proteins and makes antibodies – this does not happen immediately. Usually, the virus manages to multiply in the meantime, but the human can settle down with a temperature or worse.
Chinese, British and Russian scientists have done the same when developing their vaccines. Having taken the adenovirus, which makes us sick with ARVI, we have isolated its reduplication gene (that is, its ability to multiply) and supplemented it with the coronavirus S-protein, the same corona. 0.5 ml of Chinese vaccine contains 5×1010 virus particles. After vaccination, the chimera viruses enter a cell where they cannot multiply. In addition, a single “spare part” of the coronavirus is synthesized in the cell itself, which is unable to cause infection but provides training for the immune system.