Medicines are ingested to relieve various ailments, however there are times when some ingredients of these are mixed, it could be contradictory and therefore harmful to health, this is the case with ibuprofen with codeine.
According to the analgesic scale established by the World Health Organization (WHO), when the pain is moderate, the mixture is recommended. of weak opioids, such as codeine, with non-steroidal anti-inflammatory drugs such as
ibuprofen
.
While it is true that the effectiveness of this treatment has been proven, it has also been reported that it can cause other harm if not taken correctly. Do you ingest it or have you ingested it?
The Safety Committee (PRAC) of the European Medicines Agency (EMA) has recommended that analgesic medicines with ibuprofen and codeine warn about the serious damage that can be done to people’s health, as it could even cause death.
This recommendation was made primarily to warn people who have been taking this drug combination for a long time at higher than suggested doses. EMA recommends that they be sold with a prescription.
Risks of mixing ibuprofen with codeine
The PRAC conducted an analysis of some cases of renal, gastrointestinal and metabolic toxicity that occurred due to abuse and dependence on the combination of codeine and ibuprofen.
The mixture can damage the kidneys, they may not adequately remove acids from the blood in the urine, this could lead to very low levels of potassium in the blood and thus cause muscle weakness and dizziness. Therefore, according to the EMA, renal tubular acidosis and hypokalaemia should appear in the product prospectus as new adverse effects.
The combination of both works because the ibuprofen acts on the peripheral system, while codeine acts on the central system, for this reason the mixture of ibuprofen and codeine helps to relieve acute pain, for example, after an operation. This is important because the average doses of ibuprofen with
codeine
it helps to have an effective therapeutic result, however, but be careful, remember that it is always necessary to consult your doctor if you want to mix ibuprofen with codeineespecially if you want to ingest it for a long time.
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