New research Links Elevated Homocysteine to Loss of Aortic Elasticity,Signaling Potential Cardiovascular Risk
Graz,Austria – A new study from the Medical University of Graz has identified elevated levels of the amino acid homocysteine as a previously underestimated risk factor for cardiovascular disease,specifically linking it to a reduction in the elasticity of the aorta.Researchers found that increased homocysteine directly contributes to stiffening of blood vessels, autonomous of cholesterol levels.
The findings, published recently, highlight the importance of maintaining balanced homocysteine levels through sufficient intake of B vitamins. While high cholesterol’s impact on vessel thickening is well-established, this research demonstrates homocysteine’s distinct role in diminishing vessel elasticity – a critical component of cardiovascular health often overlooked. This revelation could lead to refined risk assessments and preventative strategies for heart disease, impacting millions.
Researchers, led by Wooden apple and Francesca Bogoni, conducted experiments on rabbits, demonstrating a clear correlation between increased homocysteine and reduced tissue elasticity in the aorta. “We deliberately left out the influence of cholesterol because we already know that too much of it thickens the blood vessels,” explained Bogoni to the Austria Press Agency. “That increased homocysteine values, however, making the blood vessels stiffer and less elastic has so far been less respected as a risk factor.”
Homocysteine levels can be readily measured through a standard blood analysis. Maintaining appropriate levels is often achievable through dietary adjustments and supplementation with B vitamins. The study underscores the need for broader awareness of homocysteine as a key indicator of cardiovascular risk, alongside conventional markers like cholesterol.
