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Genuve, thesis on preclinical effects of Alzheimer’s procedure revealed in world-class journals




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[팜뉴스=이권구 기자] GENUV (CEO Han Seong-ho) has printed the success of preclinical tests to display the neuroprotective and therapeutic effects of the treatment method of Alzheimer’s illness “SNR1611” beneath progress in “Molecular Psychiatry (Effects Variable 15.99)”, a sister journal of “Character”. claimed the 19.

‘SNR1611’ is a MAPK / ERK kinase 1/2 (MEK1 / 2) inhibitor that slows the development of Alzheimer’s illness and boosts autophagic action versus causative substances. It is the 1st content unearthed with

In accordance to the paper, as a outcome of administering “SNR1611” to the Alzheimer’s condition-induced animal design, memory and judgment improved by 56.13% and 39.30% respectively compared to the untreated team, and also fusion. autophagy-lysosome elevated to 32.67%.

At the identical time, by observing that irregular proteins these as beta amyloid are eradicated and neuronal mobile renewal and homeostasis are increased, the therapeutic impact of Alzheimer’s condition can be anticipated, Genube announced.

Han Seong-ho, CEO of GENUV, reported: “By this examine, we have shown the foundation for a new strategy to the cure of neurodegenerative disorders concentrated on neuroprotection and neurogenesis that GENUV has continually pursued.”

On the other hand, dependent on the preclinical test benefits of “SNR1611” for “SNR1611”, GENUV has been conducting medical trials for ALS in 5 significant basic hospitals in Korea, including Samsung Seoul Medical center, given that July 2020. (Unique article: https://www.nature.com/article content/s41380-022-01713-5.pdf).

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