Scientists have discovered a reliable remedy against chronic metabolic diseases
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Long-term physical exercise and sports are an effective way to avoid and even to some extent overcome some chronic metabolic diseases, such as diabetes or metabolic syndrome. This conclusion was made by scientists from the Carolina Institute in Of Sweden and the University of San Diego in the United States as a result of their research, reports Cell Reports.
The experiment involved eighteen people involved in running, cycling and other endurance exercises for at least 15 years, as well as seven men who regularly perform strength exercises.
Researchers found that with frequent physical exertion, the activity (expression) of 1,711 metabolic genes in women and 1,097 genes in men change. That is, endurance training significantly enhances the processes associated with the tricarboxylic acid cycle (Krebs cycle), which plays a key role in metabolism.
Those who performed strength exercises had only 26 genes that changed their activity. However, this does not mean at all, training does not have an effect. They can directly affect protein activity, rather than gene expression.
Experts also compared the results with data on changes in gene activity in people with metabolic syndrome and type 2 diabetes.
By the way, the subjects periodically performed the exercises for about 6-12 months, after which the situation with gene expression became similar to that observed in a new study in people performing endurance exercises for many years.
SOURCE KP.RU
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