Intense Exercise Shown too Directly inhibit Breast Cancer Cell Growth
New research suggests vigorous exercise might potentially be a core component of breast cancer treatment, going beyond its traditionally recognized role as supportive therapy. A study conducted by researchers at Edith Cowan University in Australia demonstrates that a single bout of intense exercise can directly suppress the growth of breast cancer cells.
The study, published in Breast Cancer Research and Treatment, involved 32 women who had previously overcome breast cancer. Participants were randomly assigned to either a strength training group or a high-intensity interval training (HIIT) group, completing approximately 45 minutes of exercise at a high intensity – rated 7 or 8 out of 10. Blood samples were collected before and immediately after exercise.
Researchers then exposed breast cancer cells grown in a laboratory setting to the collected blood samples. Strikingly, cells exposed to blood drawn after exercise either stopped growing or died. No such effect was observed with blood samples taken before exercise. The strength training group showed a 21% inhibition of cancer cell growth, while the HIIT group exhibited a more notable 29% suppression.
The key to this effect appears to lie in myokines – proteins released by contracting muscles. These myokines, known to have beneficial effects like reducing inflammation and boosting immune response, surged in concentration after exercise. Specifically, levels of anti-cancer myokines like decorin, interleukin-6 (IL-6), and sparc increased by up to 47%.
Notably, the level of IL-6, a myokine involved in immune function, directly correlated with the degree of cancer cell growth inhibition, with the highest increases observed after HIIT.
“The stronger the athletic stimuli, the more active the anti-cancer myokine secretion is,” explains Professor Robert Newton of Edith Cowan University. This reinforces the idea that exercise intensity is crucial.
This research builds on existing evidence of exercise’s benefits for cancer patients. A study published in the New England Journal of Medicine in June found that cancer recurrence rates were 37% lower in individuals who exercised compared to those who did not – a result comparable to some preventative medications.
Professor Newton emphasizes a shift in perspective: “Exercise is no longer a ’good activity’ added to existing chemotherapy.” However, he cautions that cancer patients should consult with a healthcare professional before beginning any new exercise program, considering the diverse nature of cancer types, individual health status, and potential complications.
(Image: Young Chinese couple running on treadmills in gym)
