Does aspirin reduce the risk of colon and rectal cancer?

A research study conducted by Harvard University scientists revealed that daily aspirin use does not reduce the risk of colon and rectal cancer among adults who start taking it after the age of 70, according to the Harvard University official website.

And a team of scientists embarked on a study that answers the question: Does aspirin for the elderly reduce the chances of colon and rectal cancer, led by Andrew T. Chan, a professor of medicine at Harvard Medical School and a gastroenterologist and head of the Clinical and Translational Epidemiology Unit at Massachusetts General Hospital, researchers conducted a pooled analysis of two large studies in the United States over a period of 20 years.These studies contributed data on the use of aspirin by more than 94,500 participants on Over the course of 35 years, providing a unique opportunity to understand the impact of lifelong aspirin use on cancer risk.

Researchers found that regular aspirin use was associated with a lower risk of colon and rectal cancer among people age 70 or older. However, this feature was only significant among people who started taking aspirin before age 70. It appears that people who started using aspirin Regularly at age 70 or older they reap no benefit.

Chan said: “There is substantial evidence that aspirin can prevent colon and rectal cancer in adults between the ages of 50 and 70 years, but it is not clear if the effect is similar in the elderly.”.”

Aspirin is one of the most well-established colorectal cancer protection agents currently recommended by the United States Preventive Services Task Force for people aged 50-59 years who have specific cardiovascular disease risk profiles due to its protective effect against heart disease..

However, aspirin was the last to experience reducing events in the elderly (ASPREE) It was reported that participants who took a daily low dose of aspirin (100 mg) after age 70 for five years actually had a 30% higher risk of dying from cancer. The vast majority of participants did not take aspirin regularly before joining the study.

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The current study confirms that taking aspirin at an older age was not associated with a reduced risk of colorectal cancer.However, it is important that there is a potential benefit for continuing aspirin if it is started at a young age. The researchers say these results “strongly indicate a possible biological difference in aspirin’s effect at older ages, which requires further research.”“.


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