Moderna’s vaccine would seem at the moment the only one able to block not only a serious course of Covid-19 in vaccinated subjects, but also the transmissibility of the virus
Protect from disease and also from contagiousness: the Moderna’s Covid-19 vaccine it would appear to be able to. The only one of the two approved by the regulatory bodies, together with that of Pfizer. There is no certainty: even in this case the only data we have are those disseminated by the manufacturers themselves and the validation of the scientific world is still lacking. As in the case of the AstraZeneca vaccine, in which the best dose was apparently discovered by a happy mistake, even in Moderna’s the protection from the transmissibility of coronavirus Sars-CoV-2 it would be due to a case of serendipity. But how did it happen? “When a clinical trial is done to approve a drug or vaccine a protocol is designed. Moderna’s protocol provided for subjecting the subjects involved in the experiment to a series of swabs at regular intervals to monitor any positivity after vaccination “, Professor Lorenzo Dagna, head of Immunology, rheumatology, allergology and rare diseases of the IRCCS San Raffaele Hospital of Milan and associate of Internal Medicine at the Vita-Salute San Raffaele University of Milan.
Was it at this point that the non-infectivity of the volunteers emerged?
“That’s right: it turned out that a significant number of people who had had contact with the virus had not developed a positive swab. This data, not yet validated by the scientific world, has led to the hypothesis that this vaccine could also control the transmission of the virus “.
The percentage data released on the effectiveness of vaccines against Covid-19, therefore, what exactly do they refer to?
“They indicate the rate of reduction of severe forms of disease. These vaccines are clearly designed to prevent disease in vaccinated individuals. The efficacy is intended as prevention of serious illness in the vaccinated person “.
Isn’t protection from Sars-CoV-2 coronavirus infection the prerogative of Pfizer and AstraZeneca vaccines?
“At the moment it is not entirely clear whether or not these vaccines render the vaccinated person unable to infect others, in addition to protecting him from the disease. However, it must be said that if the virus infects a vaccinated person it does not produce the same effect as when it infects an unvaccinated person. The stage of potential infectivity, in fact, is reduced in this case. However, this does not mean that a vaccine is impermeable to the virus. It is conceivable that at least in the early stages of the infection it can be contagious. Then the immune response it should also stop contagiousness ”.
If there is no certainty about the ability to stop contagiousness, doesn’t the idea of giving a license to vaccinated people risk being counterproductive?
“It actually might not make much sense in some ways, it’s true. It can give you a feeling of added protection that isn’t real. If the data on the potential ability to stop transmissibility of the virus in vaccinated subjects will not be confirmed will mean that the only point of no return will come when we have vaccinated such a share of the population that the spread of the virus will stop because the virus will no longer be able to find subjects to infect “.
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24 December 2020 (modified on 24 December 2020 | 12:18)
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