A team of doctors and researchers from the CHU Grenoble-Alpes has just announced its intention to launch a clinical study on the impact of hydrogen on the novel coronavirus. In order to carry out their work, they have decided to appeal to the inhabitants of the region and seek to obtain the participation of 450 volunteers, according to information revealed by Radio France.
Volunteers can make themselves known by following this link.
The people concerned must be over 60 years old, have the onset of a Covid-19 infection, but be able to stay at home. Anyone who is positive on a PCR or antigen test and who resides in Drôme, Isère, Savoie or Côte-d’Or can contact the group of doctors.
He hopes to demonstrate the effectiveness of hydrogen in preventing any “Inflammatory runaway”, which generally occurs around ten days after the onset of symptoms and results in hospitalization with heavy care.
“We have been working on hydrogen for a few years for its anti-inflammatory benefit thanks to its antioxidant properties”, explains Professor Philippe Cinquin to journalist Sophie Bécherel. “It is a small molecule, which diffuses easily and quickly in the body. It is reducing (therefore antioxidant) and rapidly absorbed by the blood and the pulmonary filter. It is able to capture reactive oxygen species, species that trigger inflammatory mechanisms ”.
Already used in China
The clinical trial to be set up will seek to demonstrate that hydrogen can also act on signaling pathways, and interrupt the succession of inflammatory reactions.
Another advantage of hydrogen is that it does not cause any negative side effects and its use has even been shown to be positive in the field of sports recovery.
Grenoble doctors believe they can prove the interest of hydrogen, this one, inhaled, being already used in Chinese hospitals.
The upcoming clinical study will involve half of patients treated with the molecule, while the other will receive a placebo. The volunteers will be offered a twenty-one-day cure consisting of twice daily drinking 250 ml of water enriched in hydrogen. “They will be monitored by teleconsultation, and they will be taught to monitor themselves with a device that measures oxygen saturation”, indicates Dr. Yoann Gaboreau, at the origin of this study.
A follow-up will be ensured at 3 months, 6 months and 12 months, in order to verify that the volunteers do not present a relapse or undesirable side effects.
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