Home » Health » Could be more virulent than B.1.1.7, US Beware of Corona Virus L452R …

Could be more virulent than B.1.1.7, US Beware of Corona Virus L452R …

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CALIFORNIA Varian virus Corona alarming discoveries were discovered at a time when outbreaks in California were intensifying, including the major plague in San Jose where an air-powered Christmas tree costume caused 90 people were infected , according to news reports.

Scientists don’t yet know whether the variant, called L452R, is more transmissible than other types of SARS-CoV-2. the virus that causes COVID-19 . But its presence in several unrelated outbreaks has health officials on alert. Also read: A New Coronavirus Strain Will Dominate the US in March 2021

“The fact that this variant was identified in several major outbreaks in our area is a red flag and should be investigated further,” said Santa Clara County health officer Sara Cody in a statement. Live Science.

The L452R variant differs from the B.1.1.7 variant which was first discovered in Great Britain and later found in Colorado, as well as nine other US states. The researchers calculated that variant B.1.1.7 was between 50% and 74% more transmissible than the standard coronavirus strain. The new strain could dominate US Coronavirus cases in March, given its tendency to spread.

Fortunately, the vaccine will likely work against variant B.1.1.7, but it could put severe stress on the health care system. This in turn causes mortality to increase before a large part of the general population can be vaccinated.

Little is known about the L452R. The variant was first detected in May 2020, but has become increasingly common since fall. According to the Eureka Times-Standard, the L452R variant was found in about 3.8% of cases following the gene sequence in November.

In late December to early January, this variant was represented in 25.2% of the virus samples sequenced. However, relatively few samples have been sequenced, and sorting is not evenly distributed across states.

According to the Santa Clara County Department of Public Health, new variants have been found in Santa Clara County, Humboldt, Lake, Los Angeles, Mono, Monterey, Orange, Riverside, San Francisco, San Bernardino, San Diego and San Luis Obispo counties. But it’s too early to say how many cases overall in California were caused by the L452R variant.

Just because a particular variant of a virus starts to host another virus does not mean that it is more contagious. Sometimes the tension just got lucky, multiplying on its own in some spreading events leading to more infections throughout the community.

“The increase in L452R coincides with a spike in the number of Coronavirus cases in California, which allows mutations to be carried by the spike rather than causing it,” infectious disease specialist Trevor Bedford said on Twitter.

Researchers are concerned about L452R, because some of its mutations affect the viral spike protein, the key that the virus uses to enter cells. The spike protein is the target of the Pfizer, Moderna, and AstraZeneca coronavirus vaccines, as well as several promising vaccines that are still in trials, including the Novavax vaccine and the Johnson & Johnson vaccine. The mutations in the protein spike could make the SARS-CoV-2 variant less susceptible to vaccines.

“This variant carries three mutations, including L452R, in the spike protein, which the virus uses to attach to and enter cells, and is the target of two vaccines currently available in the United States,” said Charles Chiu, a virologist at the University of California, San Francisco (UCSF), which has been tracking the variant.

“Now that we know this variant is on the rise in our local community, we are prioritizing it for study. Researchers at UCSF and elsewhere will now be able to carry out important laboratory experiments to determine whether or not this virus is more contagious or affects vaccine performance,” he said. again.

Even when some people receive the coronavirus vaccine, new variants like the L452R highlight why it’s important to maintain social distancing awareness until enough people are vaccinated to slow the spread of the virus, said Erica Pan, state health official for the California Department of Public Health.

“It is too early to know whether this variant will spread faster than others, but it certainly strengthens the need for all Californians to wear masks and reduces mixing with people outside their immediate household to help slow the spread of the virus,” Pan said. in a statement urging anyone who has been exposed to the virus to isolate from others to protect themselves and their loved ones. Also read: Ahsan / Hendra Proud to Win in an Injured Condition

(iqb)

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