Sunday, December 7, 2025
Home HealthCategory: BRCA Genes and Cancer Risk

Category: BRCA Genes and Cancer Risk

Local Woman’s Double Cancer Battle ‍Fuels New⁤ Breast Cancer⁢ support Association

[city, State] – After facing a diagnosis of breast cancer not once, but twice, Fabiana ⁣[Last‌Name-[LastName-[Last‌Name-[LastName-not ‍provided in​ source]has channeled her experience into creating the Instituto Olhar Rosa, a new organization⁢ dedicated to providing emotional support, free screenings, educational lectures, and vital information for breast cancer prevention. The⁤ institute aims to⁤ connect women, volunteers, and healthcare professionals,‌ offering a beacon of ⁣hope and empowerment to those affected by⁢ the disease. ‍”My purpose⁤ is to show that​ there is life beyond⁢ cancer, we can empower ourselves,​ dream and have hope,” Fabiana stated.

The​ creation of⁤ Instituto‌ Olhar Rosa ‍stems from ‍a deeper understanding of genetic‍ predispositions to cancer, specifically relating to mutations in the BRCA1 and BRCA2 genes. These genes act as​ crucial tumor⁢ suppressors, responsible for repairing DNA errors. When a⁤ mutation occurs in either​ gene, this repair mechanism is compromised, significantly increasing⁣ cancer ‌risk.

Individuals inherit ‌two ⁣copies‍ of these genes -⁢ one from each parent. A ‍mutation in just one ‌copy follows an ​autosomal dominant inheritance pattern,‍ meaning a 50% chance exists for children to‍ inherit the​ altered gene, irrespective of gender. However, cancer⁤ progress typically requires both copies⁣ of ⁢the gene to be‌ non-functional.

Research‍ indicates⁤ a strong link between BRCA1 ⁣and BRCA2 mutations and specific cancer types. A⁣ BRCA1 ‌mutation elevates ⁤the risk of breast ⁣cancer ‍by 60% to 80%, with triple-negative breast cancer being the most frequently observed. The gene also increases ⁢the likelihood⁤ of ovarian cancer (40-60%), pancreatic cancer (up to‍ 5%), prostate cancer (7-25%), and, though less common, breast⁢ cancer in men (approximately ‍1%).

Similarly,a BRCA2 mutation increases breast cancer⁣ risk by 50-60%,often manifesting as hormonal/luminal ⁣cancer. It‌ also raises the risk⁣ of ovarian⁤ cancer (up to 20%),pancreatic cancer (10%),prostate cancer (60%),and breast cancer in men (around 7%). Notably, a BRCA2 mutation is also‌ associated with an ‍increased ​risk of melanoma.

Fabiana’s personal journey, marked by a​ double battle with breast cancer,​ underscores the importance of awareness, ⁢early detection,⁢ and support systems like the‌ Instituto Olhar Rosa. The organization’s mission is‍ to empower⁤ individuals facing similar challenges and to ⁣foster a community built on hope and resilience.

Note: I have omitted the​ last ‍name‍ of ⁢Fabiana as it was not provided⁢ in the source⁤ text. I have also added a city and state⁤ placeholder as that information⁤ was missing. The lead is written in a breaking-news style, while the body provides the evergreen context ‌of BRCA1/2 genes ⁢and cancer​ risk. All numbers and quotes are directly from the provided text.

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