Almost surpassed already the first half of the month of January, many people are still running with their new Year’s resolutions. There are for all tastes, but you just have to go to any gym to verify that the exercise practice It is at the top of the ranking of new challenges.
Some people get hooked on endorphins and persist in their efforts, until what at first looked like torture ends up becoming a necessity. However, many others end up giving up just a few months, or even a few weeks, after starting. These are individuals who want to achieve the benefits of sport, but do not support stiffness, sweat and the need for constancy. They can’t help fantasizing about a tablet that would give them all those advantages, without having to endure all that negative part. But that is impossible. Or not? Although something as wonderful as what is being written in our heads right now does not seem likely, given current knowledge of science, a team of scientists from the University of Michigan and Wayne State University is behind a protein that could lead to something relatively similar. Although to know if it is really possible there is still a lot of research ahead.
The protagonists of this story are the sestrines, a group of stress-induced proteins, with an important role antioxidant in the organism
It is known that they participate in many processes, although their exact role in some of them is not entirely clear. For example, it has been proven that it tends to build up in the muscles after exercise This would indicate that you participate in it in some way. But how?
To check, these scientists put two groups of flies Drosophila, widely used in research, to train. They did it with the help of a device, similar to a small treadmill, but adapted so that insects could fly.
After three weeks of training, they went on to verify how this had affected the flies, which were divided into a normal group and another that had been modified so that I could not synthesize this protein. As explained in a statement one of the researchers, the doctor Jun Hee Lee, normally these animals can “run” between four and six hours. However, after training these times improved in the normal group, but not in those who did not have sestrin.
It seemed that protein had an essential role in improving the resistance of flies during exercise, but more experiments were needed to verify it. Therefore, they went on to a second step in which flies participated with a overexpression of the gene that encodes it, so that they could generate a greater amount of protein in their muscles.
And here began the most curious part of the study, since they found that these insects had a greater resistance than those that had been previously trained, even without practicing all that exercise. But the thing was not there, because they also saw that they acquired improvements in your aerobic capacity, your breathing and fat burning.
On the other hand, this team has also collaborated with the doctor Pura Muñoz-Cánoves, of the Pompeu Fabra University, from Barcelona, in a study that shows that the sestrin can help prevent atrophy of immobilized muscles.
Does all these mean that that dream pill that replaces exercise can exist? Not so fast. To begin, we must not forget that these results have been obtained in flies and that, even so, they are still very early. As Lee explains, they are in an initial phase of study, in which they must overcome some handicaps, such as those related to their size: “Sestrins they are not small molecules, but we are working to find small molecule modulators of Sestrina. “
In addition, his companion, the doctor Myungjin Kim, he adds that it is still necessary to investigate to learn more about the circumstances under which it is naturally secreted. Once all this has been optimized, in the future, we could talk about treatments based on this protein, but rather aimed at people who cannot exercise for health reasons. Therefore, if you can, keep playing sports. After the laces comes satisfaction, you just have to be a little constant.
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