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Blood Clot Detection: New Trial Offers Major Advance

by DrMichaelLee

Extended CT Scans dramatically Improve Stroke Cause Detection

A groundbreaking clinical trial reveals that extending computed tomography (CT) scans to include the heart significantly enhances the detection of hidden blood clots responsible for strokes. The study, conducted by researchers at London Health Sciences Center Research Institute (LHSCRI) adn the Schulich School of Medicine & Dentistry, could revolutionize how medical professionals approach stroke diagnosis and treatment.

Improved Stroke Diagnosis with extended CT Scans

Published in The Lancet Neurology, the study demonstrates that imaging the heart within minutes of a patient’s arrival at the hospital with an acute stroke dramatically improves the ability to pinpoint the stroke’s underlying cause. This innovative approach allows for more tailored and effective treatment plans to prevent future strokes.

Did You Know? Strokes are a leading cause of long-term disability and the fifth leading cause of death in the United States, affecting nearly 800,000 peopel each year according to the Centers for Disease Control and Prevention (CDC).

identifying where the clot came from is essential as it determines the safest and most effective treatment.

Dr. Luciano Sposato

The Kathleen and Dr. henry Barnett Chair in Stroke Research

The Importance of Identifying the Stroke’s Origin

Strokes,frequently enough caused by blood clots obstructing blood flow to the brain,account for approximately 85% of all stroke cases. The LHSCRI and Schulich Medicine & Dentistry study focused on determining if CT scans, including images of the heart and aorta, could identify the causes of strokes previously classified as undetermined.

According to Dr. Luciano Sposato, head of the Southwestern Ontario Regional Stroke Centre at London Health Sciences Centre (LHSC), identifying the clot’s origin is crucial for determining the safest and most effective treatment. If the clot originates in the heart, blood thinners are typically prescribed to prevent future strokes.

Clinical Trial Results: A 500% Increase in Clot Detection

The clinical trial involved 465 patients admitted to LHSC’s University Hospital for acute stroke or transient ischemic attack treatment. The results showed that using the extended CT scan increased the detection of blood clots in the heart by 500% compared to standard imaging practices. Furthermore, the extended CT scan did not delay the completion of CT imaging in emergency situations. The study identified one clot for every 14 patients scanned using the new approach.

Pro Tip: Early diagnosis and treatment are critical in minimizing the long-term effects of a stroke. Recognizing the symptoms of a stroke and seeking immediate medical attention can significantly improve outcomes.

Dr. Rodrigo Bagur, a researcher at LHSCRI and cardiologist at LHSC, emphasized that without the extended CT scan, some blood clots might have remained undetected, leading to strokes being misclassified as having an undetermined cause.

Key Findings of the Extended CT Scan Stroke Study
Metric Result
Increase in Clot Detection 500%
Patients Scanned per Clot Found 14
Total Patients in Trial 465

Funding and Future Implications

The study received funding from the School’s Department of Medicine, The Kathleen and Dr.Henry Barnett Chair in Stroke Research, and the Saraydar Neurosciences Fund.The findings suggest a notable step forward in stroke diagnosis and prevention, possibly leading to improved patient outcomes and reduced long-term disability.

Evergreen Insights: Understanding Stroke and prevention

Stroke, also known as a “brain attack,” occurs when blood supply to the brain is interrupted or reduced, depriving brain tissue of oxygen and nutrients. This can lead to brain cell death within minutes. Strokes can be caused by a blocked artery (ischemic stroke) or the leaking or bursting of a blood vessel (hemorrhagic stroke). Transient ischemic attacks (TIAs), often called “mini-strokes,” are temporary disruptions of blood flow to the brain and serve as a warning sign for future strokes. Managing risk factors such as high blood pressure, high cholesterol, smoking, and diabetes is crucial for stroke prevention. A healthy lifestyle, including regular exercise and a balanced diet, can also significantly reduce the risk of stroke.

Frequently Asked Questions About stroke Detection and Prevention


Disclaimer: This article provides general information about stroke detection and prevention and should not be considered medical advice. Consult with a qualified healthcare professional for personalized medical guidance.

What are your thoughts on this innovative approach to stroke detection? How can we improve public awareness of stroke symptoms and prevention strategies?

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