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Because There are Severe COVID-19 Patients and Those Without Symptoms

SUKABUMIUPDATE.comCOVID-19 patients can experience deteriorating health conditions that require intensive care in the hospital. Reporting from Tempo.co, on the other hand, there are also people without symptoms or OTG and do not need treatment. Why is it different?

“There is an immediate drop, high mortality. Some are without symptoms or mild symptoms. What is the cause? Good immunity, then there is no chronic disease,” explained Nikolas Wanahita, a cardiologist from Mount Elizabeth Novena Hospital, Singapore, in a webinar “Heart Healthy & COVID-19: The Dos and Don’ts “, Friday, 21 August 2020.

In addition, there is also a role for viral load in the association with the severity of COVID-19 infection. When the virus is not in large numbers, there is time for the body’s primary immune response to work faster to stem viral replication.

Furthermore, the secondary immune response takes over to release specific cells against the virus, namely B-cells and T-cells. “The body needs time to move to a secondary immune response in about five days. They release specific cells against viruses including B-cells and T-cells to secrete specific antibodies, making the virus inactive and dying. About 1-2 weeks after infection, then we recover,” “explained Wanahita.

In a bad scenario, a large viral load causes the primary immune response to become overwhelmed so that it cannot contain the virus and an excessive cytokine storm occurs.


“Excessive primary immune response production, cytokines will attack the body itself, causing inflammation or excessive inflammation. This is dangerous, causing the condition of people with COVID-19 to drop quickly,” he explained.

Apart from viral load, the use of masks can be a determining factor for the severity of COVID-19 versus only mild symptoms or no symptoms. When someone coughs or has a cold (possibly COVID-19) wearing a mask and keeping a distance when around other people who are also masked, the number of coronaviruses getting into people’s noses and mouths is smaller.

If later people around you will catch COVID-19, then it is likely not severe, mild, or even asymptomatic. In this regard, he considered the use of masks and maintaining distance to be more effective than the lockdown strategy.

“It is not a guarantee that you will not be exposed to COVID-19, but if you wear a mask and keep your distance, the type of COVID-19 you get is mild or asymptomatic,” he explained.

source: tempo.co

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