Universal Low-Dose Aspirin Prescribing Significantly Improves Preeclampsia Prevention
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- Universal Low-Dose Aspirin Prescribing Significantly Improves Preeclampsia Prevention
new research presented at the 2025 ACOG Annual Clinical and Scientific Meeting reveals that a universal low-dose aspirin (LDA) prescribing strategy substantially increased aspirin use among pregnant women at risk for preeclampsia. The findings highlight the potential of this approach, particularly in underserved communities, to improve maternal health outcomes.
Universal Aspirin Prescribing: A Game changer
The retrospective quality improvement study, conducted at the SBH Wellness Center (SBH), transitioned from a risk-based prescribing model to a universal prescribing strategy in December 2023. This intervention considered all obstetric patients as candidates for LDA starting in the second trimester, addressing a known prescribing gap identified by the Society for Maternal-Fetal Medicine [[1]].
Did You Know? Preeclampsia affects 2-8% of pregnancies worldwide and is a leading cause of maternal and infant illness and death [[2]].
Key Study Details
Researchers analyzed the electronic health records of 116 pregnant women between february and May 2024, focusing on those at 12 to 28 weeks’ gestation. The analysis assessed whether patients met the American College of Obstetricians and Gynecologists (ACOG) criteria for LDA eligibility, had preeclampsia risk factors, and were prescribed aspirin [[3]].
The results indicated that 99% of the reviewed patients met ACOG criteria for low-dose aspirin use. The overall prescribing rate during the study period was 81%,with a slightly higher rate of 88% among patients with high-risk factors.
Dramatic Increase in Aspirin Prescription Rates
Before the intervention, the LDA prescription rate was 30%. Following an initial education-focused intervention,the rate increased to 46%. After implementing the universal prescribing strategy, the rate surged to 81%.
Pro Tip: Consult with your healthcare provider to determine if low-dose aspirin is right for you during pregnancy.
This shift from selective, risk-based prescribing to a universal strategy nearly doubled aspirin use among eligible patients. The study authors emphasized that universal presumption of aspirin candidacy could be especially beneficial in underserved, low-income, urban communities where preeclampsia risk is elevated and targeted interventions may be inconsistently applied.
Study results
| Metric | Before Intervention | After Education | After Universal Prescribing |
|---|---|---|---|
| LDA Prescription Rate | 30% | 46% | 81% |
| Patients Meeting ACOG Criteria | 99% | ||
“The rate of aspirin prescription increased from 46% in our last study to 81%, demonstrating that the shift from risk-based to universal prescription increased the number of eligible patients receiving aspirin,” the researchers concluded. “Universal presumption of LDA eligibility could be beneficial for increasing aspirin prescription in lower-income urban communities with a similar patient demographic to that of SBH.”
Understanding Preeclampsia and Low-Dose Aspirin
Preeclampsia is a serious pregnancy complication characterized by high blood pressure and potential damage to organs, most often the liver and kidneys.It can occur after 20 weeks of pregnancy or postpartum. Low-dose aspirin is often recommended for women at high risk of developing preeclampsia to help prevent the condition.
The American College of Obstetricians and Gynecologists (ACOG) provides guidelines for identifying women who may benefit from low-dose aspirin during pregnancy. These guidelines consider various risk factors, including a history of preeclampsia, chronic hypertension, and certain autoimmune diseases.
Frequently Asked Questions About Low-dose Aspirin and Preeclampsia
Is low-dose aspirin safe during pregnancy?
Low-dose aspirin is generally considered safe during pregnancy when taken as prescribed by a healthcare provider.Though, it’s essential to discuss any potential risks and benefits with your doctor.
How does low-dose aspirin help prevent preeclampsia?
low-dose aspirin is believed to help prevent preeclampsia by reducing the risk of blood clots and improving blood flow to the placenta.
Are there any side effects of taking low-dose aspirin during pregnancy?
Some potential side effects of low-dose aspirin include stomach upset and an increased risk of bleeding. Though, these side effects are generally rare.
Disclaimer: This article provides general information about low-dose aspirin and preeclampsia prevention and should not be considered medical advice.Always consult with a qualified healthcare professional for personalized guidance and treatment.
What are your thoughts on universal low-dose aspirin prescribing? How can we improve maternal health outcomes in underserved communities?
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