Sulfur Dioxide exposure Linked to Increased ALS Risk, New Study Finds
Boston, MA – A new study published in Environmental Research has established a significant link between exposure to sulfur dioxide (SO2), a pollutant commonly released from burning fossil fuels, and an increased risk of developing Amyotrophic Lateral Sclerosis (ALS). Researchers found that higher levels of ambient SO2 in residential areas correlated with a greater incidence of the neurodegenerative disease.
The analysis, conducted by Saucier et al., examined data and adjusted for socioeconomic factors, revealing SO2 as the only pollutant among those studied with a demonstrable connection to ALS. Notably, the timing of SO2 exposure proved critical; levels prior to the onset of symptoms were more indicative of risk than measurements taken years before diagnosis, suggesting a potential “point of no return” for individuals.
“This is the first study to highlight that higher levels of ambient SO2 in residential areas relate to an increased risk of ALS,” the researchers wrote.
While ALS remains a rare condition – affecting roughly 1 to 2 people per 100,000 annually worldwide – it is almost invariably fatal, with most patients succumbing within three years of diagnosis due to progressive paralysis caused by the destruction of nerve cells. The cause of ALS remains largely unknown, despite identified risk factors like vigorous physical activity and certain genetic mutations.
Scientists believe a combination of factors likely contribute to the disease’s development, and this research adds to a growing body of evidence suggesting air pollution plays a role. Previous studies have linked nitrogen dioxide (NO2) to ALS risk, but this latest analysis did not find a meaningful association after adjustments. Air pollution is already known to contribute to other serious health problems, including lung cancer and mental health issues.
The research team advocates for further examination into the effects of pollutants on ALS risk and urges tighter air quality regulations. “There is a necessity for prevention strategies and improved regulatory intervention on behalf of public health on air pollution exposure levels,” they stated.
