New COVID Variant Drives uptick in Cases, Hospitalizations – november 20, 2025
A newly identified variant of SARS-CoV-2, designated HV.1.2, is fueling a rise in COVID-19 cases and hospitalizations across the United States and Europe, health officials confirmed today, November 20, 2025. While current vaccines continue to offer protection against severe illness, preliminary data indicates HV.1.2 exhibits increased transmissibility and a degree of immune evasion, prompting renewed calls for updated booster shots and preventative measures.
The surge comes as the Northern Hemisphere enters its typical respiratory virus season, raising concerns about potential strain on healthcare systems. Experts emphasize that while HV.1.2 does not currently appear to cause more severe disease than previous variants in vaccinated individuals, the sheer volume of cases-particularly among the unvaccinated and those with waning immunity-is leading to increased hospital admissions. This situation underscores the ongoing need for vigilance and adaptation in the face of a constantly evolving virus.
Current Status & Key Findings (as of November 20, 2025)
* Variant Prevalence: HV.1.2 now accounts for approximately 42% of sequenced COVID-19 cases in the U.S., according to the Centers for Disease Control and Prevention (CDC). in the United Kingdom, the variant comprises roughly 38% of cases, and similar trends are observed in France and Germany.
* Symptoms: Symptoms associated with HV.1.2 are largely consistent with previous variants, including fever, cough, sore throat, fatigue, and loss of taste or smell. however, some reports suggest a higher incidence of gastrointestinal symptoms, such as nausea and diarrhea.
* Vaccine Effectiveness: Updated COVID-19 vaccines, formulated to target XBB.1.5 and its sublineages, provide important protection against severe illness, hospitalization, and death from HV.1.2. However, vaccine effectiveness against symptomatic infection is reduced compared to earlier variants. The CDC recommends that everyone aged six months and older receive an updated 2025-2026 COVID-19 vaccine, regardless of prior vaccination status.
* Hospitalization Rates: Hospitalization rates have increased by 18% nationwide over the past two weeks, with the most significant increases observed in regions with lower vaccination rates. As of november 19, 2025, over 30,000 individuals are hospitalized with COVID-19 in the U.S.
* Severity: While HV.1.2 appears to cause similar levels of severity as previous variants in vaccinated individuals, unvaccinated individuals and those with underlying health conditions remain at higher risk of severe outcomes.
* Transmission: HV.1.2 is more transmissible than previous variants,meaning it spreads more easily from person to person. This is attributed to mutations in the virus’s spike protein, which enhance its ability to bind to human cells.
Recommendations & preventative Measures
Health officials are urging individuals to take the following steps to protect themselves and others:
* Get Vaccinated: Receive an updated 2025-2026 COVID-19 vaccine.
* Practice Good Hygiene: Wash hands frequently with soap and water for at least 20 seconds.
* Wear a Mask: Consider wearing a high-quality mask (N95 or KN95) in crowded indoor settings, especially if you are at high risk of severe illness.
* Improve Ventilation: Increase airflow in indoor spaces by opening windows or using air purifiers.
* Stay Home if Sick: If you are experiencing symptoms of COVID-19, stay home and get tested.
* Test and Treat: Utilize available testing resources and consult a healthcare provider if you test positive for COVID-19 to discuss treatment options,