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Vaccine benefits vs. vaccination complications

by Dr. Michael Lee – Health Editor

Neurological Society Highlights Emerging Evidence of Vaccine Benefits, Including​ Potential Dementia Protection & Cancer treatment Enhancement

Berlin,‌ Germany – New research presented ⁣at the German Society for Neurology (DGN) congress reveals growing evidence ‍supporting⁤ the broad health benefits of‍ vaccination, extending beyond ‌customary infection prevention to include potential​ protection against neurodegenerative diseases like⁣ dementia and even enhancing⁣ cancer ‌immunotherapy. These ⁢findings, shared today, underscore the evolving understanding of vaccine impact and their role in bolstering overall public health.

The DGN, representing over ‍13,000 neurologists, emphasized recent studies ‌demonstrating a causal⁣ link⁢ between ⁢herpes⁣ zoster vaccination and a ⁢reduced incidence of dementia. A⁣ medRxiv preprint by Eyting⁣ et al.[5] published May 25, 2023, and updated in Nature May 2025 [doi: 10.1038/s41586-025-08800-x], provides evidence suggesting vaccination against shingles ⁢may prevent⁢ a proportion of dementia cases. Simultaneously, research published ⁤in Nature on October 22, 2025 [doi: 10.1038/s41586-025-09655-y] indicates that SARS-CoV-2 mRNA vaccines can‍ sensitize tumors to immune checkpoint blockade, perhaps improving cancer treatment outcomes.

These discoveries build upon established⁤ knowledge of vaccine efficacy in preventing infectious diseases and highlight the complex ‍interplay between the immune system and long-term health. While vaccination, like any ⁢medical intervention, carries potential complications, the DGN stresses the importance of informed ⁢decision-making based on ⁣the latest scientific ⁢evidence. The society actively ​promotes research and education to ​ensure optimal​ neurological healthcare in Germany.

Founded in 1907 ​and based in Berlin, the⁤ DGN serves as a key scientific and⁣ medical ‌resource, engaging​ in health policy discussions and supporting the advancement of neurological⁣ science. Further information about the DGN congress and its presentations is available at https://www.dgn.org/dgn-kongress.

Contact:

Dr. Bettina Albers
Head of⁣ the DGN‌ press office
Tel.: ​+49(0)174 2165629
Email: presse@dgn.org

References:

[5] Eyting⁢ M,‍ Xie M, heß S, Geldsetzer P.Causal evidence that herpes ⁣zoster vaccination prevents a ⁢proportion of dementia cases. medRxiv [Preprint]. 2023 ⁣May ⁣25:2023.05.23.23290253. doi: 10.1101/2023.05.23.23290253. Update‍ in: Nature. 2025⁤ May;641(8062):438-446. doi: ⁤10.1038/s41586-025-08800-x. ​
[6] Grippin AJ, Marconi C, Copling S ‍et al.SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade. Nature. 2025 Oct 22. doi: 10.1038/s41586-025-09655-y.

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