Uric Acid Drugs: Risks & Medications to Watch Out For

Common Medications ⁢Can Trigger High Uric Acid, Increasing Gout Risk

Jakarta, Indonesia – Several widely prescribed medications can elevate uric acid levels in ⁣the blood,⁣ perhaps triggering gout or worsening ⁤existing symptoms, according to recent findings.Patients taking these ‌drugs should be aware of the risks and consult with their doctors.

Low-dose aspirin (75-150 mg) – commonly used for heart‍ attack and stroke prevention ‌- has ⁣been linked to ‍increased uric acid. Conversely,high-dose aspirin (over 2,000 mg daily) can reduce uric acid,but carries significant risks of bleeding ​and gastrointestinal toxicity.

Certain diuretics, notably ‌thiazide and furosemide, can also raise ​uric acid levels.However, potassium-sparing​ diuretics like ‌spironolactone pose a lower risk, though ‌medical consultation is still ​essential before use.

ACE inhibitors, frequently prescribed for high blood pressure and heart failure (examples include captopril and lisinopril),⁣ have also been shown to increase uric acid.Safer alternatives with‌ a lower risk ⁣include losartan and amlodipine.

patients undergoing chemotherapy for leukemia or lymphoma may experience a rapid increase in uric acid due to the rapid cell changes caused by the treatment. Immunosuppressive ​drugs used in ⁢conjunction with chemotherapy, such as cyclosporine and tacrolimus, further elevate gout risk.

Cyclosporine, used to prevent organ rejection in transplant patients, is known to ⁢increase uric acid. Similarly, long-term use of tacrolimus, another transplant immunosuppressant, can also contribute to elevated levels.

Individuals taking ‍cyclosporine or tacrolimus who suspect gout symptoms should ‍seek immediate⁣ medical attention.

Further data on managing high uric acid and preventing complications can be found here.