Wetherspoons has demanded time for European wines at the direction of the Brexit boss of the pub chain.
Pro Leave Campaign leader Tim Martin has kept his promise to sell more mine drinks from the UK and outside the EU, as the UK prepares for demolition in March.
This means that lovers of French, Italian and German wines have to drink elsewhere to enjoy their favorite treat.
The Brexit vote has toppled the bubble for all European wines and fizz previously available in the chain's 900 pubs and replaced with bottles from the US, Australia, Chile, New Zealand and Argentina.
In one third of the EU beers from the draft, Germany's Erdinger, Denmark's Tuborg and Staropramen from the Czech Republic were shown the door.
Bolla Pinot Grigio and Freixenet, both from Italy, Faustino VII Rioja from Spain, have been singled out.
They were replaced by the Australian brand Hardys and American Coldwater Creek, each with four wines, along with Villa Maria (made in New Zealand), Casillero del Diablo (in Chile) and Trivento Malbec (in Argentina).
The wines and beers join a list of EU-spirits excluded from the chain - last year Wetherspoons ceased to store Moet champagne and Italian Prosecco.
They were replaced by sparkling wines from Australia and England.
Mr. Martin has also stopped storing Jagermeister from Germany last year, which has been replaced by an English version called Strika - the "Jagbombs" were called "Brexit bombs" by customers.
However, Mr Martin has not yet been able to block all European beers, some of which, including Belgian favorite Stella Artois, are still widespread.
The millionaire founder Martin, 63, a fierce critic of the EU, distributed 500,000 coasters and called for Britain's resignation before the 2016 vote.
He expects Britain to thrive after the country leaves the EU with or without EU trade agreements.
Wetherspoon customers have accepted the changes.
Pensioner Peter Banks, 85, of Lewisham, South London, said, "I've noticed a change in the beers, but when the beers have improved, I think they should just have left everything as it was before."
Helen Adams, 37, of Croydon, said, "I do not care, but if every company stopped selling beer and wines from the EU, everyone in the UK would give up."
Tom Stainer of the campaign for Real Ale says the broader beer industry needs to reconsider its future after Brexit and urged the government and its customers to support British beer.
He said, "Wherever you stand in the Brexit debate, we hope that both government and consumers will support local breweries, producers and pubs in this time of uncertainty.
"Many of our tax rates for pubs and breweries are actually set at European level. We hope that the UK Government will use its exit from the EU to review this system.
"In particular, we would like a lower rate for beer sold as a barrel or bottle than in bottles or cans. This would help keep prices down in the pub and encourage beer drinkers to return to their local owner.
"We also want consumers to celebrate real ales, ciders and pears that are by nature British products.
"By choosing British beer and looking for the British hop logo on your pint - suggesting that hops are also sourced in the UK - beer drinkers can actively support companies near their home.
A Wetherspoon spokesman said, "Whether people agree or disagree with Tim's views shows that he is a man of his words.
"This is just the beginning and over the next two years there will be more drinks from around the world."